Once you start someone on ARVs, there's a predictable decline in viral load associated with it. This article from Nature Medicine has a nice figure, showing that different cell populations actually give rise to different portions of the decay curve, and as each replication within each "compartment" of cell type gets shut off by ARVs, that population's contribution to the viral load trails off, leading to the curve. (Hopefully it'll make better sense when you look at the figure!)
http://www.nature.com/nm/journal/v9/n7/fig_tab/nm0703-853_F2.html
from (http://www.nature.com/nm/journal/v9/n7/full/nm0703-853.html)
- Christopher Hurt
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